Pharmaceutical R&D partner worth your trust R & D advantages
100+ outstanding R&D technical talents
More than 10 R&D backbones of famous domestic schools
10 years of practical technical experience in organic chemical engineering
Long-term cooperation with 300+ high-quality customers
Joint laboratories of more than 10 prestigious universities
Core management directly participates in the project
Green and environmentally friendly high-quality production is guaranteed
Support personalized customization and production needs
Internet big data-driven technology development
Online + offline integrated service system
2000+ square meters of professional laboratory
4,000 square meters pilot plant
20,000 square meters production base
Continuously supply tens of thousands of high-quality stock compounds ranging from grams to tons
a) Catalytic hydrogenation reaction
Catalytic hydrogenation refers to the addition reaction of a reducing agent or hydrogen molecules to unsaturated compounds under the action of a catalyst, including the catalytic hydrogenation of alkenes, alkynes, aromatic rings, nitrogen-containing compounds, etc., which has a wide reduction range and high reaction activity, Good selectivity, fast speed, convenient post-processing, mild reaction conditions, convenient operation, economical application, so it has a wide range of applications in drug synthesis.
b) Ultra-low temperature reaction
Ultra-low temperature reaction can effectively improve the process yield and product purity. This technology has been applied in many fields and has a broad development prospect. SunwayPharm has used ultra-low temperature reaction (-80℃) technology to synthesize new molecular building blocks with diversified structures, which can enrich customers' personalized choices.
Organic fluorination technology is very important in the pharmaceutical industry. Among the 38 small molecule drugs approved by the U.S. FDA in 2018, 18 are fluorine-containing drugs. The introduction of fluorine atoms or fluorine-containing groups into drug molecules can change the permeability and metabolic stability of drug molecules, adjust their pKa and fat solubility, and affect the absorption and distribution of drug molecules and their interaction with biological targets. This has gradually become a common method for drug screening. SunwayPharm has widely applied fluorination reaction technology to the synthesis of key intermediates of related drugs and small molecules.
d) Chiral asymmetric synthesis
Asymmetric synthesis is "an organic reaction in which the achiral unit in the substrate molecule is converted into a chiral unit by the way that the reactants generate stereoisomeric products in unequal amounts". Chiral drugs account for more than 60% of the chemical drugs commonly used in the world today. Therefore, asymmetric synthesis currently plays a very important role in drug synthesis.
e) Enzyme Catalysis
SunwayPharm utilizes enzyme catalysis technology to produce high value-added key pharmaceutical intermediates, simplifying the reaction process, improving product utilization, and reducing equipment energy consumption. This technology owns a very broad prospect for the development of medicine, especially in the synthesis of key pharmaceutical intermediates.
f) Continuous reaction
SunwayPharm uses continuous reaction technology to improve purity and perform technical reaction connection efficiently, simplifying the process while ensuring the stability and safety of the operation. This technology has been applied in laboratories and customized synthesis to provide customers with efficient and quality product services.
Professional laboratories -- Shanghai and Weifang
2000 + M2
Pilot test bases -- Weifang, Kunming, Zhengzhou (photo)
4000 square meters, 20 L-200 L reactors
Production base Yantai (photo)
20000 square meters
500-3000 L reactors
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